# FDA Approves Johnson & Johnson’s Nasal Spray to Reduce Depression

> Johnson & Johnson’s newly FDA-approved nasal spray improves mental health by reducing depression and anxiety. Unlike traditional medications that can cause side effects, this spray uses a small dose to directly activate…

Published: 2025-01-28 · Desk: Latest · Source: CNBC News

Johnson & Johnson, the American pharmaceutical company, has developed a nasal spray aimed at improving mental health and reducing depression or anxiety. After extensive testing, the U.S. Food and Drug Administration (FDA) has approved the spray.

According to Johnson & Johnson, when administered in precise doses, the nasal spray can help manage conditions like Major Depressive Disorder (MDD).

Traditionally, doctors have prescribed various medications alongside counseling to treat depression, but long-term use of these medications often results in unwanted side effects.

Bill Martin, head of the Innovative Medicines division at Johnson & Johnson and a neurologist, explained that antidepressants can affect vital organs such as the heart, liver, and kidneys, and may also impact reproductive health. To address this, the company has developed a nasal spray that requires only a small dose. Once sprayed, it directly stimulates the body’s neurotransmitters, boosting mental health as its effects take hold.

Original reporting: https://www.cnbc.com/2025/01/21/fda-approves-johnson-johnson-nasal-spray-spravato-for-depression.html?fbclid=IwY2xjawIF0HBleHRuA2FlbQIxMAABHXbi0h-bnvmI-9a73zmRtf7o9dhz9k2Nq68l4HQ7ipgKIxIqdLLyLAaVaA_aem_HD2JKk766jhH6nZcSM848g
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